In the news Science studies at Clemson glossary of science terms biogenetic links on the web welcome to morris labs In the news Science studies at Clemson glossary of science terms biogenetic links on the web welcome to morris labs glossary of science terms In the news biogenetic links on the web Science studies at Clemson welcome to morris labs In the news Science studies at Clemson glossary of science terms biogenetic links on the web welcome to morris labs
glossary of science terms In the news biogenetic links on the web Science studies at Clemson welcome to morris labs
     

The following are terms commonly heard or read in discussions about Genetics, Biochemistry, and Molecular Biology.

(sources are indicated by the letters "D" and "A" by each definition. D=King, Robert C. and Stansfield, William D., A Dictionary of Genetics. A= Asimov, Isaac, The Genetic Code.)

 
  • allele : one of two (or multiple) alternative forms of a gene
 
  • amino acids: the subunits of proteins. There are twenty amino acids universally found in proteins.(D,A)
 
  • antibodies: proteins which react with invading microorganisms and the poisonous substances that they produce. Antibodies mark the foreign bodies for destruction by the immune system. (D,A)
 
  • ATP: adenosine triphosphate. An energy source for the cell (note the difference between dATP and ATP)
 
  • autosome: any chromosome that is not a sex chromosome
 
  • carbohydrates: a compound that has the general formula CxH2xOx. Common examples of carbohydrates are glucose, cellulose,glycogen, and starches.(D)
 
  • catalyst: a substance that increases the rate of a chemical reaction without being consumed. Enzymes are biological catalysts.(D,A)
 
  • chromosomes: one of the threadlike structures consisting of chromatin and carrying genetic information arranged in a linear sequence. (D)
 
  • cloning vector: often a small self-replicating DNA (for example, a plasmid) that can harbor foreign DNA.
 
  • conjugated protein: simple proteins combined, or joined, with non-protein substances. The blood protein Hemeglobin is an example, since it can be split into two seperate substances: heme, which is a simple protein, and globin, an iron-containing substance.(A)
 
  • denaturation: the loss of the native shape and arrangement of macromolecules resulting from heat, extreme pH changes, chemical treatment, etc. Denaturation of proteins often results in an unfolding of polypeptide chains, while denaturation of DNA leads to changes in its physical properties.(D,A)
 
  • deoxyribonucleic acid: DNA, the molecular basis of heredity. DNA consists of a polysugar-phosphate backbone from which the purines and pyrimidines project. According to the Watson-Crick model, DNA forms a double helix that is held together by hydrogen bonds between specific pairs of bases (thymine to adenine, and cytosine to guanine.) Each strand in the double helix is complimentary to its partner strand in terms of its base sequence.(D)
 
  • diploid: an organism or cell with 2 sets of each chromosome (2n)
 
  • electroporation: process by which cell membranes are made temporarily permeable by applying electric current (often used to introduce foreign DNA).
 
  • enzymes: proteins that catalyze, or speed up, reactions. Extremely specific, enzymes catalyze reactions involving only one or a few closely related compounds. (D)
 
  • eukaryote: the superkingdom containing all organisms that are, or consist of, cells with true nuclei bounded by nuclear envelopes and that undergo meiosis. Contrast with prokaryote, below.
 
  • gene: a hereditary unit located at a fixed position in the genome that yields a specific biological function.
 
  • gene transcription: process by which a gene is used as a template for the synthesis of a messenger RNA (which can then be translated).
 
  • gene translation: process that decodes messenger RNA for the synthesis of proteins.
 
  • genome: a complete set of chromosomes.
 
  • hydroxyl group: the oxygen-hydrogen group in certain molecules, which can be written "--OH."(A)
 
  • lipids: Any of a group of biochemicals that are variably soluble in organic solvents like alcohol and barely soluble in water. Some examples of lipds are fats and oils (like butter or olive oil,) as well as waxes.(A)
 
  • mRNA: messenger RNA
 
  • meiosis: process that leads to a reduction of chromosome number in reproductive cells to one-half the number found in somatic (non-reproductive) cells.
 
  • mitosis: process by which the nucleus of a eukaroytic cell divides
 
  • mutation: 1)the process by which a gene undergoes a structural change. 2) a modified gene resulting from mutation. (D)
 
  • nucleoprotein: a compound of nucleic acid (see below) and protein. (A)
 
  • nucleotide: one of the monometric units from which DNA and RNA are constructed, consisting of a purine or pyrimidine base, a pentose, and a phosphoric acid group. (D)
 
  • nucleic acid: used to store and transmit hereditary information in cells. The unique interaction of nucleic acids with other nucleic acids makes them ideally suited to this purpose. (D)
 
  • nucleus: the small, spheroidal, membrane-bounded central body of eukaryotic cells which contains DNA. (D, A)
 
  • peptides: a compound formed of two or more amino acids. (D)
 
  • peptide linkage: the combination of atoms that makes up the union between amino acids. (A)
 
  • polypeptides: a peptide made up of an undetermined number of amino acids. (A)
 
  • prokaryote: the superkingdom containing all microorganisms that lack a membrane-bound nucleus containing chromosomes. (D)
 
  • protein: a molecule composed of one or more polypeptide chains, each composed of a linear chain of amino acids covalently linked by peptide bonds. (D)
 
  • replication: a duplication process requiring copying from a template. (D)
 
  • restriction enzyme: an enzyme that cuts a specific DNA sequence. Often used to clone DNA.
 
  • simple protein: proteins that are "all protein," since no portion of their substance differs markedly in characteristics from any other portion. Ex.: the protein in egg white. (A)
 
  • valence: 1) in chemistry, a number representing the combining or displacing power of an atom; the number of electrons lost, gained, or shared by an atom in a compound; the number of hydrogen atoms with which an atom will combine, or which it will displace. 2. in serology, the number of antigen-combining sites on an antibody molecule. (D)


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